小沙吉醫師的部落格

對這項治療尚不了解的人可以先參考:

PRP高濃度血小板血漿的介紹 PRP(高濃度血小板血漿)治療關節疾患 

PRP, 也就是高濃度血小板, 應用在治療退化性關節炎已經在全世界都是很廣泛的另類治療。

但是在台灣由於尚未有一個統一的標準, 常常到不同的醫療院所詢問會得到許多不同的答案。

有關於"退化性關節炎一個療程該注射幾次"這個問題就是眾說紛紜。

現在, 有學者針對這個問題做了實際上的研究報告:

http://www.ncbi.nlm.nih.gov/pubmed/26233594

受試者包括Kellgren-Lawrence分級O, I~IV級分成不同的群組,

然後再分成注射PRP, 注射玻尿酸, 和注射生理食塩水等不同的群組。

PRP那組再分成打一劑, 和打三劑兩個群組。

臨床效的評量標準是採用IKDC and EQ-VAS scores:

最後發現,

• 打PRP和打玻尿酸的患者臨床效果都優於打生理食塩水的患者。(代表並不是所謂的安慰劑效應)
• 打三劑PRP的患者效果明顯優於其它的患者。
• 如果只打一劑PRP效果和打玻尿酸差不多。
• 以退化性關節炎的嚴重度來看, 愈輕微的患者打三劑PRP的效果會明顯優於只打一劑的。但是在嚴重的患者這個現象就比較看不到。

結論:

不嚴重的退化性關節炎採用三劑prp注射效果比較好。然而太嚴重的患者則差距不大, .....也許還是該考慮以人工關節置換的方式治療。

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